کتاب های Hernández-Tamames, Juan Antonio; Mato Abad, Virginia; García-Álvarez, Roberto; González-Zabaleta, Javier; Pereira-Loureiro, Javier; Álvarez-Linera, Juan

download pdf Effect of water T2 shortening in the quantification of in-vitro proton MR spectroscopy, دانلود Effect of water T2 shortening in the quantification of in-vitro proton MR spectroscopy,Hernández-Tamames, Juan Antonio; Mato Abad, Virginia; García-Álvarez, Roberto; González-Zabaleta, Javier; Pereira-Loureiro, Javier; Álvarez-Linera, Juan, کتاب های Hernández-Tamames, Juan Antonio; Mato Abad, Virginia; García-Álvarez, Roberto; González-Zabaleta, Javier; Pereira-Loureiro, Javier; Álvarez-Linera, Juan,Wiley 2015-05-21, لیست کتاب های Wiley 2015-05-21,WorldCat, کتاب های WorldCat

گت بلاگز Internet Ovine mesenchymal stromal cells: morphologic, phenotypic and functional characterization for osteochondral tissue engineering / دانلود فایل

مشخصات کلی Ovine mesenchymal stromal cells: morphologic, phenotypic and functional characterization for osteochondral tissue engineering

نویسنده کتاب (Author):

Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Fernández Vázquez, Tania; Fuentes Boquete, Isaac Manuel; Toro Santos, Francisco Javier de; Díaz Prado, Silvia; Blanco García, Francisco J.

انتشارات (Publisher):

PLoS ONE 2017-01-31

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

sanjurjo-rodriguez-c-castro-vin%cc%83uelas-r-hermida-gomez-t-fernandez-vazquez-t-fuentes-boquete-im-de-toro-santos-fj-et-al-ovine-mesenchymal-stromal-cells-morphologic

توضیحات خلاصه (Summary):

[Abstract] Introduction. Knowledge of ovine mesenchymal stromal cells (oMSCs) is currently expanding. Tissue engineering combining scaffolding with oMSCs provides promising therapies for the treatment of osteochondral diseases. Purpose. The aim was to isolate and characterize oMSCs from bone marrow aspirates (oBMSCs) and to assess their usefulness for osteochondral repair using β-tricalcium phosphate (bTCP) and type I collagen (Col I) scaffolds. Methods. Cells isolated from ovine bone marrow were characterized morphologically, phenotypically, and functionally. oBMSCs were cultured with osteogenic medium on bTCP and Col I scaffolds. The resulting constructs were evaluated by histology, immunohistochemistry and electron microscopy studies. Furthermore, oBMSCs were cultured on Col I scaffolds to develop an in vitro cartilage repair model that was assessed using a modified International Cartilage Research Society (ICRS) II scale. Results. oBMSCs presented morphology, surface marker pattern and multipotent capacities similar to those of human BMSCs. oBMSCs seeded on Col I gave rise to osteogenic neotissue. Assessment by the modified ICRS II scale revealed that fibrocartilage/hyaline cartilage was obtained in the in vitro repair model. Conclusions. The isolated ovine cells were demonstrated to be oBMSCs. oBMSCs cultured on Col I sponges successfully synthesized osteochondral tissue. The data suggest that oBMSCs have potential for use in preclinical models prior to human clinical studies.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Fernández Vázquez, Tania; Fuentes Boquete, Isaac Manuel; Toro Santos, Francisco Javier de; Díaz Prado, Silvia; Blanco García, Francisco J.

شناسه OCLC:979265247

Language Note:English

فهرست محتوا:1932-6203 http://hdl.handle.net/2183/18118

نویسنده : getblogs